| Schauspieler | Rolle | Synchronsprecher | ||
| James Roday | Shawn Spencer | Robin Kahnmeyer Robin Kahnmeyer | ||
| Dulé Hill | Burton 'Gus' Guster | Tobias Nath Tobias Nath | ||
| Maggie Lawson | Juliet O'Hara | Dascha Lehmann Dascha Lehmann | ||
| Timothy Omundson | Carlton Lassiter | Peter Flechtner Peter Flechtner | ||
| Corbin Bernsen | Henry Spencer | Joachim Siebenschuh | ||
| Alex Zahara | Alan Zenuk | Thomas Nero Wolff Thomas Nero Wolff | ||
| Sage Brocklebank | Officer Buzz McNab | Wanja Gerick | ||
| Kurt Fuller | Woody der Gerichtsmediziner | Frank-Otto Schenk Frank-Otto Schenk | ||
| Rachael Leigh Cook | Abigail Lytar | Giuliana Jakobeit | ||
| Michael Weston | Adam Hornstock (2. Stimme) | Bernhard Völger Bernhard Völger | ||
| Van Hansis | Adrian Viccellio | Dirk Stollberg Dirk Stollberg | ||
| C. Thomas Howell | Agent Camden Driggs | Frank Schaff Frank Schaff | ||
| Jim Thorburn | Agent Whieldon | Viktor Neumann Viktor Neumann | ||
| Kirsten Nelson | Karen Vick | Katrin Zimmermann | ||
| Liam James | Shawn Spencer (als Kind) | Oscar Räuker | ||
| Shannon Woodward | Alice Bundy | Manja Doering Manja Doering | ||
| Christine Baranski Christine Baranski | Alice Clayton | Liane Rudolph Liane Rudolph | ||
| Mena Suvari Mena Suvari | Allison Crowley | Sonja Spuhl Sonja Spuhl | ||
| Tamara Mello | Amanda | Anja Stadlober | ||
| Sara Rue | Amy Alleris | Ulrike Stürzbecher Ulrike Stürzbecher | ||
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