| Schauspieler | Rolle | Synchronsprecher | ||
| Seth Rogen Seth Rogen | Ben Stone | Tobias Kluckert Tobias Kluckert | ||
| Katherine Heigl Katherine Heigl | Alison Scott | Antje von der Ahe Antje von der Ahe | ||
| Leslie Mann Leslie Mann | Debbie | Bianca Krahl Bianca Krahl | ||
| Paul Rudd Paul Rudd | Pete | Norman Matt Norman Matt | ||
| Jason Segel | Jason | Olaf Reichmann Olaf Reichmann | ||
| Jonah Hill Jonah Hill | Jonah | Gerrit Schmidt-Foß Gerrit Schmidt-Foß | ||
| Joanna Kerns | Alisons Mutter | Heike Schroetter Heike Schroetter | ||
| Andy Dick | Andy Dick | Rainer Fritzsche Rainer Fritzsche | ||
| Bill Hader Bill Hader | Brent | Tommy Morgenstern Tommy Morgenstern | ||
| Harold Ramis Harold Ramis | Bens Vater | Jürgen Kluckert Jürgen Kluckert | ||
| Iris Apatow | Charlotte | Amelie Hintze | ||
| Louden Wainwright III | Dr. Howard | Ernst Meincke Ernst Meincke | ||
| J.P. Manoux | Dr. Angelo | Gerald Schaale Gerald Schaale | ||
| Ken Jeong | Dr. Kuni | Stefan Krause Stefan Krause | ||
| Tim Bagley | Dr. Pellagrino | Hans Hohlbein Hans Hohlbein | ||
| Eva Mendes Eva Mendes | Eva Mendes | Sandra Schwittau Sandra Schwittau | ||
| James Franco James Franco | James Franco | Kim Hasper Kim Hasper | ||
| Alan Tudyk | Jack | Frank Schaff Frank Schaff | ||
| Jessica Alba Jessica Alba | Jessica Alba | Marie Bierstedt Marie Bierstedt | ||
| Jay Baruchel Jay Baruchel | Jay | Marcel Collé | ||
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