| Schauspieler | Rolle | Synchronsprecher | ||
| Laurence Fishburne Laurence Fishburne | Dr. Ellis Cheever | Tom Vogt Tom Vogt | ||
| Kate Winslet Kate Winslet | Dr. Erin Mears | Ulrike Stürzbecher Ulrike Stürzbecher | ||
| Gwyneth Paltrow Gwyneth Paltrow | Beth Emhoff | Katrin Fröhlich Katrin Fröhlich | ||
| Matt Damon Matt Damon | Thomas Emhoff | Simon Jäger Simon Jäger | ||
| Jude Law Jude Law | Alan Krumwiede | Florian Halm Florian Halm | ||
| Marion Cotillard Marion Cotillard | Dr. Leonora Orantes | Natascha Geisler Natascha Geisler | ||
| Elliott Gould | Dr. Ian Sussman | Roland Hemmo Roland Hemmo | ||
| Bryan Cranston Bryan Cranston | Lyle Haggerty | Frank Glaubrecht Frank Glaubrecht | ||
| Dan Aho | Aaron Barnes | Frank Röth Frank Röth | ||
| Joshua Weinstein | AIMM Mitarbeiter #2 | Wolfgang Wagner | ||
| Sanaa Lathan | Aubrey Cheever | Peggy Sander Peggy Sander | ||
| Dan Flannery | Ally Hextalls Vater | Werner Ziebig | ||
| Griffin Kane | Clark Morrow | Ben Hadad | ||
| Armin Rohde | Damian Leopold | Armin Rohde | ||
| Larry Clarke | Dave | Lutz Schnell Lutz Schnell | ||
| Enrico Colantoni | Dennis French | Tobias Meister Tobias Meister | ||
| Jennifer Ehle | Dr. Ally Hextall | Andrea Aust Andrea Aust | ||
| Stef Tovar | Dr. Arrington | Karlo Hackenberger | ||
| Demetri Martin | Dr. David Eisenberg | Rainer Fritzsche Rainer Fritzsche | ||
| Jason Babinsky | Frierender Mann | Robin Kahnmeyer Robin Kahnmeyer | ||
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