| Schauspieler | Rolle | Synchronsprecher | ||
| Keanu Reeves Keanu Reeves | Neo / Thomas Anderson | Benjamin Völz Benjamin Völz | ||
| Carrie-Anne Moss Carrie-Anne Moss | Trinity | Martina Treger Martina Treger | ||
| Laurence Fishburne Laurence Fishburne | Morpheus | Tom Vogt Tom Vogt | ||
| Jada Pinkett Smith Jada Pinkett Smith | Niobe | Claudia Urbschat Mingues Claudia Urbschat Mingues | ||
| Anthony Zerbe | Councillor Hamann | Lothar Blumhagen Lothar Blumhagen | ||
| Harold Perrineau | Link | Charles Rettinghaus Charles Rettinghaus | ||
| Essie Davis | Maggie | Andrea Solter | ||
| Hugo Weaving Hugo Weaving | Agent Smith | Hans-Jürgen Wolf Hans-Jürgen Wolf | ||
| David Kilde | Agent Jackson | Tim Moeseritz Tim Moeseritz | ||
| Daniel Bernhardt | Agent Johnson | Andreas Hosang | ||
| Matt McColm | Agent Thompson | Johannes Berenz Johannes Berenz | ||
| Shane C. Rodrigo | Ajax | Sebastian Christoph Jacob | ||
| Helmut Bakaitis | Architekt | Otto Mellies Otto Mellies | ||
| Leigh Whannell | Axel | Sebastian Schulz Sebastian Schulz | ||
| Roy Jones Jr. | Ballard | Florian Halm Florian Halm | ||
| Ian Bliss | Bane | Gerald Schaale Gerald Schaale | ||
| Neil Rayment | Brinkie / Zwilling 1 | Tobias Meister Tobias Meister | ||
| Nathaniel Lees | Captain Mifune | Roland Hemmo Roland Hemmo | ||
| Gina Torres | Cas | Almut Zydra Almut Zydra | ||
| Peter Lamb | Colt | Dirk Müller | ||
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