| Schauspieler | Rolle | Synchronsprecher | ||
| Clive Owen Clive Owen | Dr. John W. Thackery | Tom Vogt Tom Vogt | ||
| André Holland | Dr. Algernon Edwards | Jan-David Rönfeldt | ||
| Juliet Rylance | Cornelia Robertson | Eva Michaelis | ||
| Jeremy Bobb | Herman Barrow | Konstantin Graudus | ||
| Eve Hewson | Lucy Elkins | Mia Diekow Mia Diekow | ||
| Chris Sullivan | Tom Cleary | Burkhard Schmeer | ||
| Michael Angarano Michael Angarano | Dr. Bertie Chickering Jr. | Tobias Schmidt | ||
| Cara Seymour | Schwester Harriet | Anne Moll | ||
| Eric Johnson | Dr. Everett Gallinger | Marius Clarén Marius Clarén | ||
| Maya Kazan | Eleanor | Celine Fontanges | ||
| David Fierro | Inspector Jacob Speight | Stephan Benson | ||
| Leon Addison Brown | Jesse Edwards | Jürgen Holdorf | ||
| Grainger Hines | Captain August Robertson | Holger Mahlich | ||
| Jennifer Ferrin | Abigail Alford | Svenja Pages | ||
| Danny Hoch | Bunky Collier | Robert Missler | ||
| Melissa Errico | Catherine Christiansen | Marion Elskis Marion Elskis | ||
| Reg Rogers | Dr. Bertram Chickering, Sr. | Joshy Peters | ||
| Matt Frewer | Dr. J. M. Christiansen | Uli Krohm Uli Krohm | ||
| Molly Price | Effie Barrow | Maria Hartmann-Schermuly | ||
| Lucas Papaelias | Eldon Pouncey | Sascha Schäfke | ||
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