| Schauspieler | Rolle | Synchronsprecher | ||
| Vera Farmiga | Dr. Anna Pou | Claudia Urbschat Mingues Claudia Urbschat Mingues | ||
| Cherry Jones | Susan Mulderick | Marianne Groß Marianne Groß | ||
| Cornelius Smith Jr. | Dr. Bryant King | Simon Pearce | ||
| Robert Pine | Dr. Horace Baltz | Walter von Hauff Walter von Hauff | ||
| Adepero Oduye | Karen Wynn | Malika Bayerwaltes | ||
| Julie Ann Emery | Diane Robichaux | Melanie Manstein | ||
| Michael Gaston | Arthur 'Butch' Schafer | Andreas Borcherding | ||
| Molly Hager | Virginia Rider | Carolin Hartmann | ||
| Stephen Bogaert | Rene Goux | Manfred Trilling | ||
| Sharron Matthews | Krankenpflegerin Cheri Landry | Astrid Martiny | ||
| Damon Standifer | Emmett Everett | Christian Jungwirth Christian Jungwirth | ||
| Brock Morgan | 585 Crewman | Uwe Thomsen | ||
| Raven Dauda | Angela McManus | Dana Geissler | ||
| Shauna Macdonald | Audrey Andrews | Tinka Kleffner | ||
| Becky Grimman | Beth / Michaels Kollegin | Bettina Zech | ||
| Aidan Devine | Bowles | Gudo Hoegel Gudo Hoegel | ||
| Terrence Clowe | Brosset | Johannes Haag | ||
| Dwayne Thomas | BStA Eddie Jordan | Fabian von Klitzing | ||
| Glenda MacInnis | Callie Fredericks | Eva-Maria Reichert | ||
| Lanette Ware | Carrie Everett | Sabine von Maydell | ||
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