| Schauspieler | Rolle | Synchronsprecher | ||
| Matthew Modine Matthew Modine | Dr. Don Francis | Johannes Berenz Johannes Berenz | ||
| Alan Alda Alan Alda | Dr. Robert Gallo | Lothar Blumhagen Lothar Blumhagen | ||
| Saul Rubinek | Dr. Jim Curran | Helmut Gauß Helmut Gauß | ||
| Sir Ian McKellen Sir Ian McKellen | Bill Kraus | Eberhard Prüter Eberhard Prüter | ||
| Walter Addison | Blood Bank Executive | Gerd Holtenau Gerd Holtenau | ||
| Clyde Kusatsu | Blood Bank Executive | Erich Räuker Erich Räuker | ||
| René Le Vant | Blood Bank Executive | Karl-Heinz Grewe | ||
| Rosemary Murphy | Blood Bank Executive | Hannelore Minkus Hannelore Minkus | ||
| Donal Logue Donal Logue | Bobbi Campbell | Markus Hoffmann | ||
| Jack Laufer | Brian McDonough | Erich Räuker Erich Räuker | ||
| Steve Martin Steve Martin | Bruder | Norbert Gescher Norbert Gescher | ||
| Richard Gere Richard Gere | Choreograph | Hubertus Bengsch Hubertus Bengsch | ||
| David Marshall Grant | Dennis Seeley | Roman Kretschmer Roman Kretschmer | ||
| Anjelica Huston Anjelica Huston | Dr. Betsy Reisz | Ulrike Lau | ||
| Christian Clemenson | Dr. Dale Lawrence | Gerald Schaale Gerald Schaale | ||
| Ken Jenkins | Dr. Dennis Donohue | Karl-Heinz Grewe | ||
| Charles Martin Smith | Dr. Harold Jaffe | Kaspar Eichel Kaspar Eichel | ||
| Ronald Guttman | Dr. Jean-Claude Chermann | Andreas Rüdiger | ||
| Lenny Wolpe | Dr. Joseph Bove | Ingolf Gorges | ||
| Patrick Bauchau | Dr. Luc Montagnier | Lothar Mann | ||
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