| Schauspieler | Rolle | Synchronsprecher | ||
| Andra Day | Ebony Jackson | Anke Reitzenstein Anke Reitzenstein | ||
| Glenn Close Glenn Close | Alberta Leecan | Kerstin Sanders-Dornseif Kerstin Sanders-Dornseif | ||
| Todd Anthony | Ahman | Oscar Räuker | ||
| Anthony B. Jenkins | Andre Jackson | Anton Hoffmann | ||
| Miss Lawrence | Asia | Jeremias Koschorz Jeremias Koschorz | ||
| Mo'Nique | Cynthia Henry | Peggy Sander Peggy Sander | ||
| Colleen Camp | Dr. Hoffsteder | Sabine Walkenbach | ||
| Dominique Toney | Janelle | Jasmin Arnoldt Jasmin Arnoldt | ||
| John Shepard | leitender Krankenhausadministrator | Bernd Vollbrecht Bernd Vollbrecht | ||
| Omar Epps | Melvin | Dietmar Wunder Dietmar Wunder | ||
| Kimberly Russell | Mrs. Ross | Agnes Hilpert | ||
| Juanita Jennings | Mrs. Tucker | Judith Steinhäuser Judith Steinhäuser | ||
| Caleb McLaughlin | Nate Jackson | Julian Tennstedt Julian Tennstedt | ||
| Tasha Smith | Pastorin Powell | Anna Dramski Anna Dramski | ||
| Nealla Gordon | Psychiaterin | Frauke Poolman | ||
| Aunjanue Ellis | Rev. Bernice James | Natascha Geisler Natascha Geisler | ||
| Demi Singleton | Shante Jackson | Marie Hinze | ||
| Ellis Hobbs IV | Trey | Oscar Räuker | ||
| N. N. | Geldeintreiber | Michael Noack | ||
| N. N. | Patty Duke / Neely O'Hara | Ilka Willner | ||
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