| Schauspieler | Rolle | Synchronsprecher | ||
| Leigh Whannell | Adam | Kim Hasper Kim Hasper | ||
| Shawnee Smith | Amanda Young | Gundi Eberhard Gundi Eberhard | ||
| Bahar Soomekh | Dr. Lynn Denlon | Cathlen Gawlich Cathlen Gawlich | ||
| Donnie Wahlberg | Eric Matthews | Torsten Michaelis Torsten Michaelis | ||
| Tobin Bell Tobin Bell | Jigsaw / Jonathan Kramer | Bodo Wolf Bodo Wolf | ||
| Dina Meyer | Kerry | Cathrin Vaessen | ||
| Alan Van Sprang | Chris | Johannes Berenz Johannes Berenz | ||
| Niamh Wilson | Corbett | Jamie Lee Blank | ||
| Debra McCabe | Danica | Isabelle Schmidt | ||
| Kim Roberts | Deborah | Almut Zydra Almut Zydra | ||
| Costas Mandylor | Det. Lt. Mark Hoffman | Thomas Nero Wolff Thomas Nero Wolff | ||
| Angus Macfadyen | Jeff | Wolfgang Wagner | ||
| Betsy Russell | Jill Tuck | Isabella Grothe | ||
| Jane Luk | Krankenschwester | Sabine Walkenbach | ||
| Dylan Trowbridge | Notarzt | Frank Ciazynski | ||
| Tim Burd | Obi | Nicht synchronisiert | ||
| Lyriq Bent | Officer Rigg | Jan-David Rönfeldt | ||
| Barry Flatman | Richter Halden | Frank-Otto Schenk Frank-Otto Schenk | ||
| Mpho Koaho | Tim | Julien Haggége Julien Haggége | ||
| J. LaRose | Troy | Thomas Schmuckert Thomas Schmuckert | ||
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